ScientiaCME Free CME Courses

  • FREE

    ScientiaCME Acute hepatic porphyria: optimizing pharmacotherapeutic management strategies

    Activity Description / Statement of Need:
    In this online, self-learning activity:

    Acute hepatic porphyria (AHP) is an umbrella term for four types of acute porphyria, the most severe of which is acute intermittent porphyria (AIP). An estimated 80% of AHP cases are AIP, which is an inherited autosomal dominant condition that results from mutations of the third enzyme of heme synthesis, porphobilinogen deaminase. In the Western countries, it is estimated that approximately 1 in 2000 individuals are carriers of the relevant mutated genotype, although the majority have latent AIP and are clinically asymptomatic. Acute attacks occur in less than 10% of the at-risk population, reflecting the role of environmental factors, such as alcohol use, infections, and hormonal changes, among others. AHP symptoms are believed to be caused by ALAS1-mediated accumulation of ALA and PBG in the liver and bloodstream, leading to neurotoxicity.

    Target Audience:
    The following HCPs: hematologists and gastroenterologists; physician assistants, nurse practitioners, and pharmacists who practice in any of the aforementioned areas of specialties; and any other healthcare professionals with an interest in or who clinically encounter patients with AHP.

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    • Cost: Free
    • Credit hours: 1
    • CME credits awarded by: ScientiaCME
    • Format: On-Demand Online
    • Material last updated: July 06, 2023
    • Expiration of CME credit: July 06, 2025
  • FREE

    ScientiaCME Addressing persistent health disparities head-on with culturally competent care

    Activity Description / Statement of Need:
    In this online, self-learning activity:

    Health disparities are defined as “preventable differences in the burden of disease, injury, violence, or opportunities to achieve optimal health that are experienced by populations that have been disadvantaged by their social or economic status, geographic location, and environment.” According to the landmark 2002 report by the Institute of Medicine, Unequal Treatment: Confronting Racial and Ethnic Disparities in Health Care, even when access-related factors are accounted for, racial and ethnic minorities receive a lower quality of health care than White patients. The Agency for Healthcare Research and Quality also releases an annual National Healthcare Quality and Disparities Report showing White patients receive a better quality of care and experience better health outcomes compared to non-Whites.

    Target Audience:
    HCPs including: physicians, physician assistants, nurses, pharmacists, and any other clinician involved in providing patient care.

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    • Cost: Free
    • Credit hours: 1
    • CME credits awarded by: ScientiaCME
    • Format: On-Demand Online
    • Material last updated: June 15, 2023
    • Expiration of CME credit: June 15, 2025
  • FREE

    ScientiaCME Advanced systemic mastocytosis: from recognition to treatment

    Activity Description / Statement of Need:
    In this online, self-learning activity:

    Systemic mastocytosis (SM) is a heterogeneous group of disorders caused by proliferation of abnormal clonal mastocytes, which accumulate in the skin and/or other organ systems. Mastocytosis, including SM, was reclassified as a distinct disease subtype in 2016, when the World Health Organization (WHO) removed mastocytosis from the myeloproliferative neoplasm (MPN) group. The WHO defines 5 SM subtypes, ranging from indolent SM, which is associated with mild symptoms and near-normal life expectancy, to mast cell leukemia, which is an aggressive hematologic malignancy associated with median survival of less than 1 year.

    Target Audience:
    HCPs including: hematology/oncology specialists, allergists, and clinical immunologists, dermatologists; physician assistants, nurse practitioners, and pharmacists who practice in those areas of specialty; and any other healthcare professionals with an interest in or who may clinically encounter patients with systemic mastocytosis.

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    • Cost: Free
    • Credit hours: 1
    • CME credits awarded by: ScientiaCME
    • Format: On-Demand Online
    • Material last updated: September 28, 2023
    • Expiration of CME credit: September 28, 2025
  • FREE

    ScientiaCME Advances in the management of acute lymphoblastic leukemia (ALL) in children and adolescents

    Activity Description / Statement of Need:
    In this online, self-learning activity:

    Acute lymphoblastic leukemia (ALL) is one of a group of malignancies marked by unregulated growth of immature lymphoid cells. Each year, over 6,500 new cases are diagnosed, and ALL claims an estimated 1,390 lives in the same timeframe. The incidence of ALL peaks at 1 to 4 years of age, and it accounts for three quarters of cases of acute leukemia in children. The signs and symptoms of ALL are nonspecific and can include fatigue, malaise, or palpitations associated with anemia; fever with or without infection due to leukopenia or leukocytosis; petechiae; and bleeding or bruising of the oral mucosa or skin. Although the precise etiology of ALL remains unknown, some cases have been associated with exposure to ionizing, toxic chemicals, and herbicides; genetic conditions such as Down syndrome, Fanconi syndrome, neurofibromatosis; and viruses like human T-lymphotropic viruses 1 and 2 and Epstein-Barr virus.

    Target Audience:
    HCPs including: pediatric hematology-oncology, hematology, oncology, pathology, and those who otherwise commonly care for or clinically encounter patients with ALL.

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    • Cost: Free
    • Credit hours: 1
    • CME credits awarded by: ScientiaCME
    • Format: On-Demand Online
    • Material last updated: September 23, 2023
    • Expiration of CME credit: September 23, 2024
  • FREE

    ScientiaCME Best practice in the systemic treatment of advanced and recurrent endometrial cancer

    Activity Description / Statement of Need:
    In this online, self-learning activity:

    Endometrial cancer is the most common gynecologic cancer and the fourth most common cancer in women living in the United States, with approximately 66,000 cancers of the uterine corpus diagnosed every year and over 12,000 associated deaths. The vast majority of women are diagnosed with endometrial cancer after the age of 50, and risk factors are obesity, level of physical activity, increasing age, and the presence of a variety of comorbid, chronic health conditions. The costs associated with endometrial cancer may amount to tens of thousands of dollars per patient, depending on the stage of disease upon diagnosis. The five-year survival rate for patients with localized disease is 95%, but survival rates drop to 18% in patients with advanced disease, one in ten patients is diagnosed with distant cancer, representing an area of ongoing clinical need.

    Target Audience:
    HCPs including: medical, including gynecologic, oncologists; physician assistants, nurse practitioners, and pharmacists who practice in oncology; and other clinicians who commonly encounter patients with advanced or recurrent endometrial cancer.

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    • Cost: Free
    • Credit hours: .75
    • CME credits awarded by: ScientiaCME
    • Format: On-Demand Online
    • Material last updated: August 25, 2023
    • Expiration of CME credit: August 25, 2024
  • FREE

    ScientiaCME Challenges and updates in the management of von Hippel-Lindau disease and related tumors

    Activity Description / Statement of Need:
    In this online, self-learning activity:

    Von Hippel-Lindau (VHL) disease is a rare genetic condition caused by an autosomal dominant mutation of the VHL tumor suppressor gene. The mutation gives rise to an abnormal VHL protein that cannot bind effectively to protein HIF-1α, leading to the transcription of multiple genes and upregulation of growth factors. The condition is thought to affect between 1 in 39,000 and 1 in 91,000, with a birth incidence of between 1 in 36,000 and 1 in 45,500. Diagnosis of VHL disease is established when the patient undergoes genetic testing and a pathogenic mutation of the VHL gene is found. Genetic testing is typically conducted if the patient has a family history of VHL or they are showing signs of VHL-related symptoms. VHL disease is characterized by tumors and cysts growing in various parts of the body, including the brain, spine, eyes, inner ears, pancreas, kidneys, adrenal glands, and reproductive tract. The clinical presentation of the disease is different in every patient and is impossible to predict, so close monitoring is required. Complications of the disease are on a case-by-case basis, but patients with VHL are at an increased risk of developing some cancers, particularly clear cell renal cell carcinoma (RCC) and pancreatic cancer.

    Target Audience:
    HCPs including: Medical and genitourinary oncologists, urologists, and nephrologists; physician assistants, nurse practitioners, and pharmacists specializing in the aforementioned areas of specialty; and any other HCPs involved or interested in treatment of VHL disease.

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    • Cost: Free
    • Credit hours: .75
    • CME credits awarded by: ScientiaCME
    • Format: On-Demand Online
    • Material last updated: September 08, 2023
    • Expiration of CME credit: September 08, 2024
  • FREE

    ScientiaCME Contemporary approaches and emerging therapies for the management of respiratory syncytial virus in infants and young high-risk children

    Activity Description / Statement of Need:
    In this online, self-learning activity:

    Respiratory syncytial virus (RSV) is a highly contagious pathogen belonging to the Pneumoviridae family that circulates seasonally with other respiratory viruses. The majority of the population is exposed to RSV, but children under the age of two years and older adults are at the greatest risk of significant morbidity and mortality. RSV infections are responsible for approximately 60-80% of pediatric bronchiolitis and 40% of pediatric pneumonia cases and are a major cause of global hospitalization and mortality. Almost 70% of children are exposed to RSV during their first year of life, and 90% are exposed within their first two years, resulting in an estimated 427,000 emergency department visits and 1.6 million pediatrician visits annually.

    Target Audience:
    HCPs including: Obstetricians, pediatricians, and family medicine physicians; physician assistants, nurse practitioners, pharmacists specializing in pediatrics; and any other HCPs involved or interested in the management of RSV in infants and high-risk children.

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    • Cost: Free
    • Credit hours: 1
    • CME credits awarded by: ScientiaCME
    • Format: On-Demand Online
    • Material last updated: October 15, 2023
    • Expiration of CME credit: October 15, 2025
  • FREE

    ScientiaCME Integrating novel PrEP options as a step toward ending the HIV epidemic

    Activity Description / Statement of Need:
    In this online, self-learning activity:

    According to the Centers for Disease Control and Prevention (CDC), there are nearly 1.2 million people aged 13 years and older living with HIV (PLWH) in the U.S. Since the beginning of the HIV epidemic in the 1980s, advances in public health initiatives and treatments have considerably lengthened the life expectancy of PLWH, while simultaneously reducing transmission and diagnosis of new cases. Nonetheless, an estimated 31,000 people are infected with HIV each year in the United States, with the highest incidence in people from underserved and marginalized communities. As a result, a key component of the federal Ending the HIV Epidemic (EHE) strategy is to prevent new HIV infections by expanding use of evidence-based interventions.

    Target Audience:
    HCPs including: Infectious disease specialists, primary care physicians, and public health professionals; physician assistants, nurse practitioners, and pharmacists who practice in infectious disease; and any other HCPs with an interest in or who clinically encounter HIV.

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    • Cost: Free
    • Credit hours: 1
    • CME credits awarded by: ScientiaCME
    • Format: On-Demand Online
    • Material last updated: July 22, 2023
    • Expiration of CME credit: July 22, 2024