Question 1 of 6
USMLE Step 2 Sample Question 1

A 7-year-old female presents shortly after her birthday with erythematous, indurated, scaly plaques over her earlobes in a symmetric pattern. Her mother reports that the patient recently received a pair of earrings from her older cousin as a birthday present. What is the mechanism of this reaction?

  • AAnaphylactic (type I)
  • BCytotoxic (type II)
  • CImmune complex-mediated (type III)
  • DCell-mediated/delayed (type IV)
  • EAutoimmune disease (type V)
USMLE Step 2 Sample Question 2

A 57-year-old female presents for a second opinion of a left breast lesion that had been diagnosed as “eczema” by her regular nurse practitioner, which briefly improved after a short course of topical steroids. On physical exam, there is an erythematous, scaly lesion involving the left breast nipple-areolar complex with weeping drainage. What is the next step in the patient’s management?

  • ABilateral breast ultrasound
  • BPunch biopsy of nipple, followed by bilateral mammography
  • CMaintenance of regular annual mammography appointments
  • DOral corticosteroids
  • ELeft breast MRI


Provide your email to see your results and get exclusive discounts on additional board review questions.

USMLE Step 2 Board Review Questions

Our USMLE Step 2 Board Review Questions are specifically focused on challenging content. We selected the hardest questions to make sure that you are maximizing your study time. Each question comes with a detailed explanation that serves as a mini-lecture for reviewing key content.


Developed by top faculty and practicing physicians, BoardVitals helps thousands of doctors prepare for board certification exams and complete their CME requirements. BoardVitals is trusted by leading medical institutions including Harvard, Yale, Mt. Sinai, and Duke.


“I tutor students at a local medical school on the weekends and questions are a huge part of my teaching strategy. I've found BoardVitals' questions are excellent teaching tools, because the answer explanations are always on point and provide good clinical context. I would recommend your Step 2 Question Bank to any medical student studying for USMLE who wishes to supplement their core notes and their learning, overall.”

KM, resident physician at Glendale Adventist