Special Notice!! Looking for reviewers to help keep the List up-to-date. |
The sites described on this page are primarily concerned with rheumatology. You will find other online CME sites and courses partially concerning rheumatology at the main online CME site. |
Cleveland Clinic Biologic Therapies in Autoimmune and Inflammatory Disease States
|
This site is based on a meeting that took place in August 2007. After studying the content, you should be able to: review and describe immunoregulatory pathways including the roles of T-cell and B-cell activation and effector function, cytokine biology, and immunologic central mechanisms in the pathogenesis of autoimmune and inflammatory diseases; differentiate the mechanisms of action, efficacy, and toxicity of varying classes of biologic therapeutics (TNF, T-cell, B-cell, and directed agents); apply state-of-the-art management strategies to patients with varied autoimmune and inflammatory diseases; recognize and diagnose refractory states of autoimmunity and inflammation including rheumatoid arthritis, vasculitis, psoriasis, and inflammatory bowel disease states; and evaluate the risks and benefits of using biologic therapies as options in patients with refractory autoimmune and/or inflammatory diseases. |
Cleveland
Clinic Current and Emerging Trials, Mechanisms, and Agents in B-Cell–Directed Therapies |
These activities concern new therapies in the treatment of autoimmune rheumatic diseases (ARDs). After completing this course, you should be able to: cite the key clinical features of recent advances in B-cell biology as they relate to autoimmune rheumatic diseases; review advances in molecular biology that contribute to the understanding of the pathogenesis of autoimmune rheumatic diseases; discuss recently published clinical data relating to the usage of B-cell–directed therapies for rheumatoid arthritis; and examine current approaches to the usage of B-cell–directed therapeutics in rheumatoid arthritis. |
Cleveland
Clinic: Hepatic Effects of Biologic Agents: Current and Future Issues in the Treatment of Rheumatoid Arthritis |
A single monograph, Hepatic Effects of Biologic Agents: Current and Future Issues in the Treatment of Rheumatoid Arthritis. The monograph is a report of a discussion between a rheumatologist and a hepatologist of the hepatic effects of biologic agents in the treatment of rheumatoid arthritis and their potential for the treatment of viral hepatitis. |
Cleveland Clinic: Immunocompetence and Biologic Therapies: Assessing Risks and Preventing Complications from Infections |
This program intends to strengthen the ability of rheumatologists to manage the challenge of balancing therapeutic immune suppression and the risk of infectious complications. Lecture titles are: Importance of Assessing Immunocompetence in Biologic Drug Development; Relative Risks of Serious Bacterial and Opportunistic Infections Among Biologics: Results of Randomized Trials and Observational Studies; The Effect of Biologic Agents on Humoral Immunity: Significance of Immunoglobulins and Response to Vaccines; Infectious Complications of Biologic Therapies: Preventive and Therapeutic Strategies; and Immunocompetence and Biologic Therapies: Assessing Risks and Preventing Complications from Infections - Panel Discussion. |
Cleveland Clinic Neuroinflammatory Diseases in Rheumatology |
After completing this course, you should be able to: classify neuropsychiatric complications of SLE and describe the sequence, order, and interpretation of neurodiagnostic testing needed to accurately diagnose these complications; differentiate the common clinical subsets of CNS vasculitis from their important mimics and describe the interpretation and limitations of common neurodiagnostic testing used for its evaluation; identify the common clinical and electrodiagnostic features of vasculitis neuropathy and associate and correlate such findings to neurovascular pathologic findings; and define the role of immunosuppressive and biologic therapies in the pathogenesis of opportunistic CNS infections. |
Cleveland
Clinic: Rheumatoid Arthritis eJournal Club |
This eJournal club will engage RA clinicians in an examination, discussion and assessment of the most recent peer-reviewed, RA literature. Areas of focus will include emerging approaches to improve patient function and quality of life, and to reduce mortality. This new series has only one activity at present: Certolizumab Pegol Plus Methotrexate Is Significantly More Effective Than Placebo Plus Methotrexate in Active Rheumatoid Arthritis: Findings of a Fifty-Two–Week, Phase III, Multicenter, Randomized, Double-Blind, Placebo Controlled, Parallel-Group Study. Keystone E, et al. Arthritis Rheum. 2008;58:3319-3329 |
Cleveland
Clinic: Rheumatoid Arthritis Virtual Grand Rounds |
This series contains bimonthly discussions on the management of complicated RA patient cases that encompass diverse treatment challenges. Current lectures include: Prevention of Infection in Rheumatoid Arthritis Patients Receiving Biologic Agents; Rheumatoid Arthritis and Imaging; Treating a Patient with RA and Hepatitis B or C; Therapeutic Issues in Rheumatoid Arthritis and Pregnancy; Rheumatoid Arthritis and Heart Failure; Managing Rheumatoid Arthritis Patients with an Inadequate Response to TNF Inhibitors; Rheumatoid Arthritis and Malignancy: Associations, Effects of Treatment, and Discussion of Options for Patients with Prior Cancer; and The Management of Difficult Rheumatoid Arthritis. |
Clinical Conundrum: Use of COX-2 Inhibitors, nsNSAIDs and ASA in Patients with Cardiovascular Risk
|
Four brief lectures on the use of these medications in patients with cardiovascular risk. After completing this course, you should be able to: discuss the cardiovascular risks associated with non-selective and selective NSAIDs; review & compare data on the effects of aspirin therapy in conjunction with NSAID therapies; summarize the UGI complications associated with nsNSAIDs and selective NSAIDs and the impact of concomitant administration of ASA; and analyze the benefit:/risk profile of CV vs. GI events. |
Extra Miles
(Rheumatoid Arthritis Cyberounds) | Extra Miles is an interactive running game on the roles and mechanisms of action of T cells and B cells, and their impact on the diagnosis, treatment and management of rheumatoid arthritis patients who do not respond to current "biologic" TNF-alpha inhibitors. |
Foundation for Osteoporosis Research and
Education (FORE) | Use Internet Explorer to view these five presentations related to osteoporosis: Cytokine Networks in Systemic & Focal Bone Loss; Can Medications Inhibit & Even Heal Erosions in RA?; Epidemiology of Bone Loss in Inflammatory Arthritis and Secondary to Glucocortoids; New Paradigm in Osteoporosis Assessment: Absolute Fracture Risk Determination; and Novel Therapies Directed at Molecular Targets for Bone Loss. |
Medscape
Rheumatology
|
CME activities of special interest to rheumatologists. Medscape
contains a variety of educational formats:
|
Projects In Knowledge Advanced Certificate Program IV: Bridging Cultural Differences to Improve HBV Treatment in Asian and Other Diverse Communities
|
The fourth year of this program features 19 courses presented online over one year, and offers up to 18 credits. The curriculum contains the latest information on HBV virology and genotyping, screening and diagnosis in the Asian community, AASLD, Keeffe, and APASL hepatitis B virus treatment guidelines, and current and emerging treatment strategies. It will also help clinicians understand the impact of cultural differences in the management of HBV infection, with particular focus on the Asian and Pacific Islander communities. |