Physician CME

In this online, self-learning activity:

Polycythemia vera (PV) is an uncommon hematologic malignancy belonging to BCR-ABL1-negative myeloproliferative neoplasms (MPNs), characterized by activating mutations in JAK2 that cause the proliferation of malignant hematopoietic stem and progenitor cells. PV is characterized by erythrocytosis, thrombocytosis, leukocytosis, and splenomegaly, with approximately 50% of patients presenting symptoms such as fatigue, headache, visual disturbances, and pruritus at diagnosis. Others may be asymptomatic and diagnosed incidentally through blood tests, and as the disease progresses, individuals often experience worsening symptoms along with new ones, including early satiety and inactivity. Approximately 148,000 individuals in the United States have PV; the annual incidence of PV ranges from 0.01 to 2.61 per 100,000 individuals, while its prevalence varies from 45 to 57 per 100,000. Primarily affecting older individuals, PV has an overall median age of 61 years, with less than 10% of cases occurring in those under 40 years old.

In this online, self-learning activity:

Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic connective tissue disorder characterized by dysregulated chondrogenesis, with heterotopic ossification (HO) being the most typical feature. The global prevalence of FOP is estimated at 1.43 per million individuals, with a U.S. prevalence of 0.88 per million. FOP develops due to a mutation in the ACVR1 gene encoding the active receptor-like kinase (ALK2), with unique presenting symptoms including great toe malformations and the development of swelling in several areas of the body within the first decade of life.

In this online, self-learning activity:

Human immunodeficiency virus (HIV) is a retrovirus that preferentially targets CD4+ T lymphocytes, driving chronic immune activation, CD4+ depletion, and heightened vulnerability of people living with it (PLWH) to opportunistic infections and certain malignancies. Early, guideline-concordant primary care engagement is essential to mitigate these risks and optimize long-term outcomes. Contemporary antiretroviral therapy (ART) recommendations from major panels provide multiple highly effective, well-tolerated options that enable durable viral suppression when initiated promptly and supported over time.

In this online, self-learning activity:

Pulmonary hypertension (PH) comprises five etiologic groups; Group I, pulmonary arterial hypertension (PAH), is a precapillary entity defined hemodynamically by right‑heart catheterization: mean pulmonary artery pressure >20 mm Hg, pulmonary artery wedge pressure ≤15 mm Hg, and pulmonary vascular resistance ≥3 Wood units. PAH is uncommon but consequential; estimates place U.S. prevalence near 10.6 per million, with contemporary data showing rarity yet meaningful population burden. Sex differences are notable—women predominate, while men may experience more severe trajectories—underscoring the need for sex‑aware assessment. Multinational reviews suggest incidence and prevalence remain non‑trivial, with enduring morbidity and mortality despite therapeutic gains.

This brief accredited CME activity uses a quiz-based microlearning platform to present a patient case scenario and related questions, allowing clinicians to quickly test their knowledge of the essential components of evaluating patients with metastatic colorectal cancer to the liver and selecting an appropriate treatment strategy. They can then compare their responses with those of their peers. Rationale for correct answers and key educational takeaways are provided via video clips from expert faculty.

Using a quiz-based format, this accredited CME activity offers a brief, interactive microlearning experience centered around a clinical case scenario, enabling clinicians to quickly test their understanding of weight-related eligibility criteria for kidney transplantation, compare their answers with peer responses, and gain expert insights through video commentary. Faculty explore how obesity affects transplant candidacy, evaluation strategies, and potential interventions to optimize patients for transplant, as well as provide key takeaways to support informed, patient-centered clinical decisions.

In this brief 15-minute activity, you will:

– Follow the case of a patient who presents with foot drop and no other medical conditions
– Choose optimal management approaches by answering nongraded questions within the activity (answers are collected for informational purposes only and used to assess the effectiveness of this educational activity)
– See how your answers compare with those of your peers
– View video clips providing expert insights

In this 15-minute activity, meet 2 patients with arm pain, one of whom also presents with neck pain. How would you manage these patients? This accredited activity uses an interactive, quiz-driven microlearning format to explore clinical case scenarios with targeted questions, allowing clinicians to quickly assess their knowledge. Clinicians can compare their responses with those of their peers and receive expert guidance through video commentary.

This accredited activity reviews advancements in lung transplant surgery, with a focus on robotic lung transplant and ex vivo lung perfusion.

This 30-minute Symposium from the 2025 Fall Clinical Dermatology Conference for PAs and NPs explores how to personalize psoriasis management and improve treatment selection based on patient specific history.

“With biologics we have gotten more specific. Before we had this big sweeping sword and now we have these precise, tiny knives. That is where we are at with going from previous agents to IL-23 and IL-17 blockers.” – Dr. Harrison Nguyen.

This activity is supported by educational grants from AbbVie, Johnson & Johnson and Ortho Dermatologics, and SUN Pharmaceutical Industries, Ltd.

Recent advancements in refractive surgery techniques and technologies continue to evolve, offering expanded options for managing patients with refractive errors. Lens-based refractive surgery presents an alternative to traditional laser-based approaches, providing a broader range of correctable refractive errors and enabling personalized treatment plans tailored to each patient’s unique needs. In this CE monograph, experts will explore the current role of lens-based refractive surgery for myopia correction, compare it with traditional laser-based refractive procedures, and share valuable clinical insights on selecting the most suitable patients for lens-based versus laser-based refractive surgery in the context of myopia treatment.

This course will help you improve your critical reasoning, evaluation, and communication skills through an intensive case review designed to help you zero in on what is most clinically relevant for diagnosis, surgical approach, and case management across all essential areas of general surgery. The course covers standard care-relevant cases utilizing a mock oral exam format. In addition, we’ve recorded virtual one-on-one mock oral sessions between individual volunteers and our best Faculty, covering all required topic areas to bring them to you. When you register for our virtual mock oral course, you receive access to stream the condensed video library (12 hours) PLUS two complimentary virtual private mock orals. As a unique aspect of our review, we will also offer 16 hours of live, unscripted mock oral exams followed by interactive Q&A sessions.

In addition, participants may purchase as many additional virtual private mock oral sessions.

*Faculty and topic availability may be limited over time.”

This interactive prep course is designed to help you practice and build confidence as we prepare you to conquer your Boards in the virtual setting where you will take the exam. Our expert faculty and excellent teachers in their respective fields have prepared thousands of candidates for their Boards. Each mock examiner has adapted and utilized the SCORE Curriculum in creating scenarios for your 30-minute mock oral sessions. You practice going over three scenarios in each mock oral session. As in the actual exam, you have 7 minutes for each scenario, leaving 9 minutes for detailed feedback and teaching points.
Accreditation Statement
The Osler Institute is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
*restrictions apply
* CME Credit and Osler guarantee policy are non-applicable.

*Faculty and topic availability may be limited over time.

Enhance your critical reasoning and evaluation skills in an intensive case review course designed to focus on the most clinically relevant aspects of diagnosis, treatment approach, and patient management in all key areas of Ophthalmology. The course begins with a lecture on the critical reasoning and communication skills necessary to succeed in the Oral Certification exam, which will be emphasized through recorded mock oral exams that are available for viewing.

These recorded mock orals cover standard care cases and feature a half-hour format with feedback. Additionally, participant volunteers and some of our top faculty members were recorded in 25-minute virtual simulations of the Oral Board process, followed by faculty critiques. A special “Optic Pearls” lecture will highlight the essential aspects of optics required for both the certification exam and your medical practice.

Course fees include participation in two private virtual mock orals scheduled over the three days of the course. Participants may also purchase additional mock orals if desired; however, availability may be limited close to the start of the course.

This interactive preparation course is designed to help you practice and build confidence as you get ready to conquer your Boards in a virtual exam setting. Our expert faculty, along with experienced instructors in their respective fields, have successfully prepared thousands of candidates for their Boards. Each mock examiner has tailored scenarios based on the content outline to create engaging 30-minute mock oral sessions. During these sessions, you will work through multiple timed scenarios, receive direction and presentation cues, and be given time for detailed feedback, including teaching points and take-home messages.

The course fees cover participation in five private virtual mock oral exams scheduled throughout the three days of the course. Participants may purchase additional mock oral sessions; however, topic availability may be limited as the course start date approaches.

This comprehensive review aims to enhance your clinical knowledge and help you pass your Pathology AP and CP exams, whether for certification or continuing certification. The course emphasizes evidence-based practice and board-relevant standards of care, incorporating new concepts, testing strategies, quality control, and laboratory management skills. Many previous participants have found that the course improved their diagnostic and evaluation skills and helped them identify specific areas of weakness for further self-study.

The course includes didactic lectures with review questions at the end of each topic, an e-syllabus containing all PowerPoint presentations, and designated Q&A sessions covering Blood Bank procedures and Clinical Chemistry. Lectures on Anatomical Pathology will be held from Saturday through Tuesday, while Clinical Pathology topics will be covered from Tuesday through Friday. Tuesday is designated as an overlap day, featuring both Anatomic and Clinical Pathology topics throughout the day.

The webinar will be delivered via Zoom Cloud Meetings, facilitating interaction between participants and faculty. For the best experience, it is recommended to use a computer with a strong internet connection to join the webinar. All participants will receive complimentary streaming access to the course recording until June 7, 2026.

In this online, self-learning activity:

Thalassemias belong to a group of recessively inherited blood disorders characterized by little or no hemoglobin production and chronic anemia of varying severity. Alpha thalassemia (AT) is most commonly found in people of Mediterranean, Middle Eastern, Asian, and North African descent. Worldwide, 5% of people are AT carriers, with a much higher prevalence in certain regions (e.g., up to 23% in Southeast Asia). AT is typically caused by deletions of one or more α-globin genes, leading to reduced or abolished α-globin production; non-deletional forms of AT can also occur and are generally more severe. The loss of functional α-globin disrupts the globin chain equilibrium, leading to excess γ- and β-globin chain formation and causing ineffective erythropoiesis. Patients with both deletional and non-deletional types of AT can develop various clinical complications, such as iron overload, gallstones, impaired liver function, osteoporosis, and elevated uric acid levels. Cardiopulmonary and skeletal deformities are common in patients from countries in the Western hemisphere who have elevated ferritin, while infections are the leading complication and cause of death in patients who live in countries in the Eastern hemisphere and have transfusion-dependent thalassemia.

In this online, self-learning activity:

Hemophilia is a genetic disease caused by mutation of one of the genes for coagulation proteins leading to dangerous, uncontrolled bleeding. In hemophilia B, a mutation in the gene for factor IX (FIX) leads to an endogenous deficiency in the clotting factor. The incidence of hemophilia B is the same across race and ethnic groups, affecting approximately 1 out of every 30,000 male births.

The therapeutic landscape for diabetic macular edema (DME) is rapidly evolving with the introduction of novel treatments, protocols, and delivery methods designed to improve visual outcomes and reduce patient burden. Advancements include extended injection protocols that are the result of longer durations of action for recently approved therapies and the Port Delivery System with ranibizumab—a sustained drug delivery system that was approved in February of 2025 for the treatment of patients with DME. In this Rapid Response activity, experts in the field discuss the latest clinical reports on the treatment of DME as presented at the Angiogenesis 2025 meeting. Faculty engage in a fast-paced review of the latest data on DME treatments, protocols, and modalities and discuss how these updates affect their own clinical practices and the broader field of retinal care.

Uveitic macular edema (UME) is the leading cause of visual impairment in patients with uveitis, particularly in patients with noninfectious uveitis. Noninfectious uveitis affects up to 30% of patients with uveitis and can lead to vision-threatening complications, such as macular ischemia, if left untreated. Corticosteroids remain the first-line treatment, delivered via systemic, periocular, or intravitreal routes, but their long-term use is limited by significant ocular and systemic adverse effects. Advances in treatment, such as long-acting intravitreal corticosteroid implants, immunomodulatory therapies, and novel delivery systems like suprachoroidal injections, have improved outcomes by reducing adverse effects and enhancing visual acuity and macular anatomy. Despite these advancements, treatment regimens remain challenging due to limited robust evidence, variability in patient response, and adverse event profiles. In this CE activity, expert faculty compare corticosteroid delivery systems based on dosage, administration, and the ability to personalize treatment. They also review the latest clinical evidence for UME treatments and their ability to improve long-term outcomes.