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Question 1: What is the neurobiological mechanism of mirtazapine?


  1. Alpha2-adrenergic receptor antagonist

  2. Dopamine (D2) receptor antagonist

  3. Norepinephrine reuptake inhibitor

  4. Histamine (H1) receptor antagonist

  5. Serotonin (5HT2) receptor agonist


Reference: 1. Sadock BJ, Kaplan HI, Sadock VA. Kaplan & Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry. Philadelphia, PA: Wolter Kluwer/Lippincott Williams & Wilkins. 2007. 2. Stahl S. Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 5th ed. New York, NY: Cambridge University Press. 2014.


Question 2: Among the general population, which of the following disorders is most commonly comorbid in anorexia nervosa?


  1. Somatic disorders

  2. Personality disorders

  3. Major depressive disorder

  4. Bipolar disorders

  5. Obsessive-compulsive disorder


Reference: Hudson JI, et al. The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biol Psychiatry. 2007;61(3):348.


Psychiatry Question Bank

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