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Question 1: Which of the following best describes the schematics depicted below?

  1. Matrix assisted laser desorption absorption time of flight mass spectrometer

  2. High performance liquid chromatography

  3. Mass spectrometer

  4. Normal phase chromatography

  5. X-ray absorption near edge structure


Reference: Zhaoyang Liu, et al. Optimization of MALDI-TOF. Journal of American Society for Mass Spectrometry. 2005.16(4).


Question 2: A 65-year-female presents to the emergency room with vaginal bleeding. She has a history of uterine cancer and is suffering from therapy-related AML.The patient is admitted and is found to be thrombocytopenic. Multiple platelet transfusions are administered, but the patient’s vaginal bleeding continues. The bleeding finally resolves when the patient is started on Amicar (aminocaproic acid). A transfusion medicine consult is ordered to determine if the patient is suffering from platelet refractoriness.The clinical team is instructed to obtain a platelet count one hour after she is transfused in order for you to calculate a Corrected Count Increment (CCI). If 4 x 1011 platelets are transfused while patient’s body surface area is 1.8 m2 and the increase in post transfusion platelet count is 25,000/μL, then:

  1. The CCI is 7,000/ μL.

  2. The CCI is 9,000/μL.

  3. The CCI is 11,250/μL.

  4. The CCI is 20,000/μL.


References: Roback JD, Grossman BJ, Harris T, and Hillyer CD, editors. Technical Manual. 17th ed. Bethesda, MD: AABB, 2011.

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